Yes you can. There is a extension method included called MultiCharacterWildcard() that appends an appropriate... well... multi character wildcard (an asterisk for Lucene) to the end of a string.

Your example of "abo" matching "about" is easily reproducable. However, trying to match "bout" in "about" will not perform well, and is not recommended. You should try to stick to "starts with" searches if possible.

You could also try Fuzzy(), which is based on keyword similarity rather than an exact starting match. That said, I found it gave pretty unexpected results, especially for short words, and it was hard to tune the "fuzziness". I went back to ending keywords with a wildcard and the results were much more logical.

Here is a topic that documents my journey into the world of Examine in which I make a bunch of stupid mistakes, but ultimately came out with a great solution. Hope it helps!