Hi Christopher,

Here's how I'm doing it and all seems to be working fine:

public partial class Global : UmbracoApplication
{
 
        protected override void OnApplicationStarted(object sender, EventArgs e)
        {
            base.OnApplicationStarted(sender, e);
            RegisterRoutes(RouteTable.Routes);
        }

        protected void Application_Start()
        {
            AreaRegistration.RegisterAllAreas();
        }

        public static void RegisterRoutes(RouteCollection routes)
        {
            routes.IgnoreRoute("{resource}.axd/{*pathInfo}");

            // Add your routes here as normal
        }
    }

Hope this helps,
Tom 

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