I have an Umbraco7 site with this structure

En

 -Home

 -Page1

Es

 -Home

 -Page1

It

 -Home

 -Page1

And I want when you browse to 

www.mydomain.com/en/home.aspx to have the culture and culture-ui set to en or en-GB

www.mydomain.com/it/home.aspx to have the culture set to it or it-IT 

etc

I am not sure how to set up my web config so that each subdirectory would have a different globalisation setting.

From the globalisation settings I can change the culture of the entire application but I want my culture to be set per directory.

I tried setting the hostnames and that partly works but it affects the URLs and I want the same hostname to apply to multiple cultures per subdirectory

Any idea if that's possible?